In vivo cytotoxic T-lymphocyte induction may take place via CD8+ T helper lymphocytes
نویسندگان
چکیده
منابع مشابه
In vivo cytotoxic T-lymphocyte induction may take place via CD8 T helper lymphocytes.
Immunization of mice with peptide constructs, consisting of a determinant recognized by T cytotoxic cells colinearly linked to a determinant recognized by T helper cells (TDc-TDh) was able to induce cytotoxic T lymphocytes in vivo. Interestingly, this induction could be achieved in the absence of adjuvant in non-depleted as well as in CD4(+)-cell-depleted BALB/c mice. In the latter case, induct...
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ژورنال
عنوان ژورنال: Research in Immunology
سال: 1995
ISSN: 0923-2494
DOI: 10.1016/0923-2494(96)80238-0